NCAA Football: Penn State at Michigan State
Mike Carter / USA TODAY Sports

Struggling Big Ten teams meet up at noon ET on Saturday when the Penn State Nittany Lions travel to take on the Michigan Wolverines. The Nittany Lions are 0-5 on the season, while the Wolverines are 2-3. Jim Harbaugh's side narrowly escaped against Rutgers last week in a come-from-behind 48-42 triple-overtime victory.

William Hill Sportsbook lists the Wolverines as 1.5-point favorites, down from opening at -3.5, in the latest Michigan vs. Penn State odds. The over-under for total points expected has moved down to 56.5 after opening at 60.5. Before finalizing any Penn State vs. Michigan picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $3,600 for $100 players on its top-rated college football picks against the spread. It is also a sizzling 44-23 on all top-rated picks through 12 weeks of the 2020 college football schedule, returning over $1,200 in profit already. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Michigan vs. Penn State. You can head to SportsLine to see its picks. Here are several college football odds for Penn State vs. Michigan:

  • Michigan vs. Penn State spread: Michigan -1.5
  • Michigan vs. Penn State over-under: 56.5 points
  • Michigan vs. Penn State money line: Michigan -120, Penn State +100

What you need to know about Michigan

Harbaugh's sixth year in Ann Arbor started out promising with a blowout win over Minnesota, a team that was ranked at the time. The Wolverines, however, were upset by rival Michigan State 27-24 the following week. They then lost big to Indiana and Wisconsin, before getting back in the win column last week. On the season, Michigan is just 1-4 against the spread and hasn't covered in its last four.

Freshman quarterback Cade McNamara is expected to get the start in this matchup. He tossed four touchdowns against Rutgers and seemed to give the offense more efficiency than Joe Milton. The Wolverines will likely need to score frequently to pick up this cover since their defense has given up at least 38 points in the last three outings. 

What you need to know about Penn State

Meanwhile, the matchup between Penn State and the Iowa Hawkeyes last Saturday was not a total blowout, but with Penn State falling 41-21 at home, it was darn close to turning into one. A silver lining for the Nittany Lions was the play of WR Jahan Dotson, who caught eight passes for one TD and 139 yards. 

One of the most thrilling moments was Dotson's 68-yard TD reception in the third quarter. Dotson has 31 catches for 527 yards and six touchdowns now on the season and he'll be a tough matchup for a Michigan secondary that has given up at least 300 yards through the air in three of the last four games.

How to make Michigan vs. Penn State picks

The model has simulated Michigan vs. Penn State 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that is hitting in nearly 70 percent of simulations. You can only see the pick at SportsLine.

So who wins Michigan vs. Penn State? And which side of the spread cashes in nearly 70 percent of simulations? Visit SportsLine now to see which side of the Penn State vs. Michigan spread to jump on, all from the advanced model that is up over $3,600 on its top-rated college football spread picks, and find out.